Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have a similar burden of rare protein-truncating variants

We analyze the exome sequences of approximately 8,000 children with autism spectrum disorder (ASD) and/or attention-deficit/hyperactivity disorder (ADHD) and 5,000 controls, and we find that ASD and ADHD have a similar burden of rare protein-truncating variants in evolutionarily constrained genes, b...

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Detalles Bibliográficos
Autores principales: Satterstrom, F. Kyle, Walters, Raymond K., Singh, Tarjinder, Wigdor, Emilie M., Lescai, Francesco, Demontis, Ditte, Kosmicki, Jack A., Grove, Jakob, Stevens, Christine, Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Palmer, Duncan S., Maller, Julian B., Nordentoft, Merete, Mors, Ole, Robinson, Elise B., Hougaard, David M., Werge, Thomas M., Mortensen, Preben Bo, Neale, Benjamin M., Børglum, Anders D., Daly, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884695/
https://www.ncbi.nlm.nih.gov/pubmed/31768057
http://dx.doi.org/10.1038/s41593-019-0527-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884695/
https://www.ncbi.nlm.nih.gov/pubmed/31768057
http://dx.doi.org/10.1038/s41593-019-0527-8

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