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Non-coding RNAs in cancers with chromosomal rearrangements: the signatures, causes, functions and implications
Chromosomal translocation leads to the juxtaposition of two otherwise separate DNA loci, which could result in gene fusion. These rearrangements at the DNA level are catastrophic events and often have causal roles in tumorigenesis. The oncogenic DNA messages are transferred to RNA molecules, which a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884712/ https://www.ncbi.nlm.nih.gov/pubmed/31361891 http://dx.doi.org/10.1093/jmcb/mjz080 |