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Non-coding RNAs in cancers with chromosomal rearrangements: the signatures, causes, functions and implications

Chromosomal translocation leads to the juxtaposition of two otherwise separate DNA loci, which could result in gene fusion. These rearrangements at the DNA level are catastrophic events and often have causal roles in tumorigenesis. The oncogenic DNA messages are transferred to RNA molecules, which a...

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Detalles Bibliográficos
Autores principales: Han, Cai, Sun, Lin-Yu, Wang, Wen-Tao, Sun, Yu-Meng, Chen, Yue-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884712/
https://www.ncbi.nlm.nih.gov/pubmed/31361891
http://dx.doi.org/10.1093/jmcb/mjz080