Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts

BACKGROUND: Late-stage breast cancer preferentially metastasises to bone; despite advances in targeted therapies, this condition remains incurable. The lack of clinically relevant models for studying breast cancer metastasis to a human bone microenvironment has stunted the development of effective t...

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Detalles Bibliográficos
Autores principales: Lefley, Diane, Howard, Faith, Arshad, Fawaz, Bradbury, Steven, Brown, Hannah, Tulotta, Claudia, Eyre, Rachel, Alférez, Denis, Wilkinson, J. Mark, Holen, Ingunn, Clarke, Robert B., Ottewell, Penelope
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884811/
https://www.ncbi.nlm.nih.gov/pubmed/31783893
http://dx.doi.org/10.1186/s13058-019-1220-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884811/
https://www.ncbi.nlm.nih.gov/pubmed/31783893
http://dx.doi.org/10.1186/s13058-019-1220-2

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