miR-644-5p carried by bone mesenchymal stem cell-derived exosomes targets regulation of p53 to inhibit ovarian granulosa cell apoptosis

BACKGROUND: This article aims to reveal the therapeutic effects and potential mechanisms of bone mesenchymal stem cell (BMSC)-derived exosomes on premature ovarian failure (POF). METHODS: Exosomes were collected from BMSCs and were used to treat cisplatin-induced POF mouse models. Pathological chang...

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Detalles Bibliográficos
Autores principales: Sun, Bo, Ma, Yujia, Wang, Fang, Hu, Linli, Sun, Yingpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884862/
https://www.ncbi.nlm.nih.gov/pubmed/31783913
http://dx.doi.org/10.1186/s13287-019-1442-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884862/
https://www.ncbi.nlm.nih.gov/pubmed/31783913
http://dx.doi.org/10.1186/s13287-019-1442-3

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