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miR-644-5p carried by bone mesenchymal stem cell-derived exosomes targets regulation of p53 to inhibit ovarian granulosa cell apoptosis
BACKGROUND: This article aims to reveal the therapeutic effects and potential mechanisms of bone mesenchymal stem cell (BMSC)-derived exosomes on premature ovarian failure (POF). METHODS: Exosomes were collected from BMSCs and were used to treat cisplatin-induced POF mouse models. Pathological chang...
Autores principales: | Sun, Bo, Ma, Yujia, Wang, Fang, Hu, Linli, Sun, Yingpu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884862/ https://www.ncbi.nlm.nih.gov/pubmed/31783913 http://dx.doi.org/10.1186/s13287-019-1442-3 |
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