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Autologous mitochondrial microinjection; a strategy to improve the oocyte quality and subsequent reproductive outcome during aging

Along with the decline in oocyte quality, numerous defects such as mitochondrial insufficiency and the increase of mutation and deletion have been reported in oocyte mitochondrial DNA (mtDNA) following aging. Any impairments in oocyte mitochondrial function have negative effects on the reproduction...

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Detalles Bibliográficos
Autores principales: Mobarak, Halimeh, Heidarpour, Mohammad, Tsai, Pei-Shiue Jason, Rezabakhsh, Aysa, Rahbarghazi, Reza, Nouri, Mohammad, Mahdipour, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884882/
https://www.ncbi.nlm.nih.gov/pubmed/31798829
http://dx.doi.org/10.1186/s13578-019-0360-5