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Syndecan-1 suppresses cell growth and migration via blocking JAK1/STAT3 and Ras/Raf/MEK/ERK pathways in human colorectal carcinoma cells

BACKGROUND: Syndecan-1 (SDC-1) is a crucial membrane proteoglycan, which is confirmed to participate in several tumor cell biological processes. However, the biological significance of SDC-1 in colorectal carcinoma is not yet clear. An objective of this study was to investigate the role of SDC-1 in...

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Detalles Bibliográficos
Autores principales: Wang, Shaojun, Zhang, Xiaofei, Wang, Guimei, Cao, Bin, Yang, Hong, Jin, Lipeng, Cui, Mingjuan, Mao, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884902/
https://www.ncbi.nlm.nih.gov/pubmed/31783811
http://dx.doi.org/10.1186/s12885-019-6381-y