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PRL2 serves as a negative regulator in cell adaptation to oxidative stress

High levels of ROS cause oxidative stress, which plays a critical role in cell death. As a ROS effector protein, PRL2 senses ROS and controls phagocyte bactericidal activity during infection. Here we report PRL2 regulates oxidative stress induced cell death. PRL2 senses oxidative stress via highly r...

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Detalles Bibliográficos
Autores principales: Du, Xinyue, Zhang, Yang, Li, Xiao, Li, Qi, Wu, Chenyun, Chen, Guangjie, Guo, XiaoKui, Weng, Yongqiang, Wang, Zhaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884919/
https://www.ncbi.nlm.nih.gov/pubmed/31798830
http://dx.doi.org/10.1186/s13578-019-0358-z