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Osteopontin Mediates Cetuximab Resistance via the MAPK Pathway in NSCLC Cells

BACKGROUND: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. The high expression of osteopontin (OPN) is an important factor that aggravates drug resistance and causes a poor prognosis in this disease. Therefore, understanding the molecular mechanism of OPN is critical for...

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Detalles Bibliográficos
Autores principales: Cui, Jian, Wang, Jun, Lin, Chao, Liu, Jixiang, Zuo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884967/
https://www.ncbi.nlm.nih.gov/pubmed/32063712
http://dx.doi.org/10.2147/OTT.S228437