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Inhibition of ISG15 Enhances the Anti-Cancer Effect of Trametinib in Colon Cancer Cells
BACKGROUND: Colon cancer is one of the most common cancers worldwide. IFN-stimulated gene 15 (ISG15), a ubiquitin-like molecule, is strongly up-regulated by type I interferon as a crucial response to a variety of microbial and cellular stress stimuli. However, the role of ISG15 in colon cancer remai...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884973/ https://www.ncbi.nlm.nih.gov/pubmed/32063716 http://dx.doi.org/10.2147/OTT.S226395 |