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Inhibition of ISG15 Enhances the Anti-Cancer Effect of Trametinib in Colon Cancer Cells

BACKGROUND: Colon cancer is one of the most common cancers worldwide. IFN-stimulated gene 15 (ISG15), a ubiquitin-like molecule, is strongly up-regulated by type I interferon as a crucial response to a variety of microbial and cellular stress stimuli. However, the role of ISG15 in colon cancer remai...

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Detalles Bibliográficos
Autores principales:	Zhou, Sheng, Ren, Meilin, Xu, Huanji, Xia, Hongwei, Tang, Qiulin, Liu, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884973/ https://www.ncbi.nlm.nih.gov/pubmed/32063716 http://dx.doi.org/10.2147/OTT.S226395

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