Nrf2 Activation Protects Mouse Beta Cells from Glucolipotoxicity by Restoring Mitochondrial Function and Physiological Redox Balance

Influencing the redox balance of pancreatic beta cells could be a promising strategy for the treatment of diabetes. Nuclear factor erythroid 2p45-related factor 2 (Nrf2) is present in beta cells and regulates numerous genes involved in antioxidant defense. As reactive oxygen species (ROS) are import...

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Detalles Bibliográficos
Autores principales: Schultheis, Johanna, Beckmann, Dirk, Mulac, Dennis, Müller, Lena, Esselen, Melanie, Düfer, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885177/
https://www.ncbi.nlm.nih.gov/pubmed/31827698
http://dx.doi.org/10.1155/2019/7518510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885177/
https://www.ncbi.nlm.nih.gov/pubmed/31827698
http://dx.doi.org/10.1155/2019/7518510

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