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Long noncoding RNA MEG3 suppresses podocyte injury in diabetic nephropathy by inactivating Wnt/β-catenin signaling

BACKGROUND: Diabetic nephropathy (DN) is one of the principal complications of diabetes and podocyte injury plays an important role in the DN pathogenesis. Wnt/β-catenin signaling overactivation confers podocyte injury and promotes multiple types of renal disease. However, the underlying mechanism o...

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Detalles Bibliográficos
Autores principales: Che, Xiajing, Deng, Xin, Xie, Kewei, Wang, Qin, Yan, Jiayi, Shao, Xinghua, Ni, Zhaohui, Ying, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885352/
https://www.ncbi.nlm.nih.gov/pubmed/31799068
http://dx.doi.org/10.7717/peerj.8016