Knockdown of mitofilin inhibits autophagy and facilitates starvation-induced apoptosis in HeLa cells

OBJECTIVE(S): Mitofilin contributes to the maintenance of mitochondrial structure and functions. This study was undertaken to determine the mechanisms underlying its regulation of apoptosis. MATERIALS AND METHODS: Mitofilin was knockdowned by specific short hairpin RNA (shRNA) and the stable HeLa ce...

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Detalles Bibliográficos
Autores principales: Shen, Mengli, Wang, Li, Kuang, Lingyun, Liu, Danhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885394/
https://www.ncbi.nlm.nih.gov/pubmed/31998453
http://dx.doi.org/10.22038/ijbms.2019.36173.8617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885394/
https://www.ncbi.nlm.nih.gov/pubmed/31998453
http://dx.doi.org/10.22038/ijbms.2019.36173.8617

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