CD137 ligand feedback upregulates PD‐L1 expression on lung cancer via T cell production of IFN‐γ

BACKGROUND: The expression of PD‐L1 and its regulation in tumors remains unclear. The importance of IFN‐γ in upregulating the PD‐L1 expression in various tumors, and the effects of other essential cytokines in the tumor microenvironment (TME), need to be further elucidated. METHODS: Constitutive exp...

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Detalles Bibliográficos
Autores principales: Wang, Helin, Yan, Zhuohong, Hao, Jianqing, Yang, Bin, Wang, Jinghui, Yi, Ling, Wang, Xiaojue, Li, Shuping, Zhang, Hongtao, Zhang, Shucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885434/
https://www.ncbi.nlm.nih.gov/pubmed/31625289
http://dx.doi.org/10.1111/1759-7714.13207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885434/
https://www.ncbi.nlm.nih.gov/pubmed/31625289
http://dx.doi.org/10.1111/1759-7714.13207

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