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Vedolizumab in combined immune checkpoint therapy-induced infliximab-refractory colitis in a patient with metastatic melanoma: A case report

BACKGROUND: Dual checkpoint inhibition improves response rates in treatment naïve patients with metastatic melanoma compared to monotherapy. However, it confers a higher rate of toxicity, including immune-related colitis. Steroids may not resolve symptoms in all cases. The use of vedolizumab, a huma...

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Detalles Bibliográficos
Autores principales: Randhawa, Manreet, Gaughran, Gregory, Archer, Christine, Pavli, Paul, Morey, Adrienne, Ali, Sayed, Yip, Desmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885450/
https://www.ncbi.nlm.nih.gov/pubmed/31799150
http://dx.doi.org/10.5306/wjco.v10.i10.350