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The long non-coding RNA TUG1-miR-9a-5p axis contributes to ischemic injuries by promoting cardiomyocyte apoptosis via targeting KLF5

Non-coding RNAs participate in many cardiac pathophysiological processes, including myocardial infarction (MI). Here we showed the interplay between long non-coding RNA taurine-upregulated gene 1 (lncR-TUG1), miR-9a-5p (miR-9) and Krüppel-like factor 5 (KLF5). LncR-TUG1 was upregulated in ischemic h...

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Detalles Bibliográficos
Autores principales: Yang, Di, Yu, Jie, Liu, Hui-Bin, Yan, Xiu-Qing, Hu, Juan, Yu, Yang, Guo, Jing, Yuan, Ye, Du, Zhi-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885510/
https://www.ncbi.nlm.nih.gov/pubmed/31787746
http://dx.doi.org/10.1038/s41419-019-2138-4