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Macrophage-associated pro-inflammatory state in human islets from obese individuals

Obesity is associated with inflammatory macrophages in insulin responsive tissues and the resulting inflammatory response is a major contributor to insulin resistance. In insulin-producing pancreatic islets, the intra-islet accumulation of macrophages is observed in patients of type 2 diabetes (T2D)...

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Detalles Bibliográficos
Autores principales: He, Wei, Yuan, Ting, Maedler, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885511/
https://www.ncbi.nlm.nih.gov/pubmed/31787760
http://dx.doi.org/10.1038/s41387-019-0103-z