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NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling

Inflammatory bowel disease (IBD) is one of the most common diseases in the gastrointestinal tract related to aberrant inflammation. Pyroptosis, which is characterized by inflammasome formation, the activation of caspase-1, and the separation of the N- and C-terminals of GSDMD, might be related to IB...

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Detalles Bibliográficos
Autores principales: Chen, Xueliang, Liu, Ganglei, Yuan, Yuanyuan, Wu, Guotao, Wang, Shalong, Yuan, Lianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885517/
https://www.ncbi.nlm.nih.gov/pubmed/31787755
http://dx.doi.org/10.1038/s41419-019-2157-1