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Rod bipolar cells dysfunction occurs before ganglion cells loss in excitotoxin-damaged mouse retina
Progressive degeneration of retinal ganglion cells (RGCs) will cause a blinding disease. Most of the study is focusing on the RGCs itself. In this study, we demonstrate a decline of the presynaptic rod bipolar cells (RBCs) response precedes RGCs loss and a decrease of protein kinase Cα (PKCα) protei...
Autores principales: | Shen, Yumeng, Luo, Xue, Liu, Shiliang, Shen, Ying, Nawy, Scott, Shen, Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885518/ https://www.ncbi.nlm.nih.gov/pubmed/31787761 http://dx.doi.org/10.1038/s41419-019-2140-x |
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