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Glycerol induces G6pc in primary mouse hepatocytes and is the preferred substrate for gluconeogenesis both in vitro and in vivo

Gluconeogenesis (GNG) is de novo production of glucose from endogenous carbon sources. Although it is a commonly studied pathway, particularly in disease, there is a lack of consensus about substrate preference. Moreover, primary hepatocytes are the current gold standard for in vitro liver studies,...

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Detalles Bibliográficos
Autores principales: Kalemba, Katarzyna M., Wang, Yujue, Xu, Huiting, Chiles, Eric, McMillin, Sara M., Kwon, Hyokjoon, Su, Xiaoyang, Wondisford, Fredric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885632/
https://www.ncbi.nlm.nih.gov/pubmed/31645433
http://dx.doi.org/10.1074/jbc.RA119.011033