Novel study design to assess the efficacy and tolerability of antiseizure medications for focal‐onset seizures in infants and young children: A consensus document from the regulatory task force and the pediatric commission of the International League against Epilepsy (ILAE), in collaboration with the Pediatric Epilepsy Research Consortium (PERC)

High‐quality placebo‐controlled drug trials for focal‐onset seizures in infants and children younger than 4 years have become increasingly difficult to perform because of eligibility constraints and onerous study designs. Traditional designs used in these populations require a high baseline seizure...

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Detalles Bibliográficos
Autores principales: Auvin, Stéphane, French, Jacqueline, Dlugos, Denis, Knupp, Kelly G., Perucca, Emilio, Arzimanoglou, Alexis, Whalen, Ed, Shellhaas, Renée A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Special Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885693/
https://www.ncbi.nlm.nih.gov/pubmed/31819909
http://dx.doi.org/10.1002/epi4.12356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885693/
https://www.ncbi.nlm.nih.gov/pubmed/31819909
http://dx.doi.org/10.1002/epi4.12356

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