PACAP and Other Neuropeptide Targets Link Chronic Migraine and Opioid-induced Hyperalgesia in Mouse Models*

Chronic use of opioids can produce opioid-induced hyperalgesia (OIH), and when used to treat migraine, these drugs can result in increased pain and headache chronicity. We hypothesized that overlapping mechanisms between OIH and chronic migraine occur through neuropeptide dysregulation. Using label-...

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Detalles Bibliográficos
Autores principales: Anapindi, Krishna D.B., Yang, Ning, Romanova, Elena V., Rubakhin, Stanislav S., Tipton, Alycia, Dripps, Isaac, Sheets, Zoie, Sweedler, Jonathan V., Pradhan, Amynah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885698/
https://www.ncbi.nlm.nih.gov/pubmed/31649062
http://dx.doi.org/10.1074/mcp.RA119.001767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885698/
https://www.ncbi.nlm.nih.gov/pubmed/31649062
http://dx.doi.org/10.1074/mcp.RA119.001767

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