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PACAP and Other Neuropeptide Targets Link Chronic Migraine and Opioid-induced Hyperalgesia in Mouse Models*
Chronic use of opioids can produce opioid-induced hyperalgesia (OIH), and when used to treat migraine, these drugs can result in increased pain and headache chronicity. We hypothesized that overlapping mechanisms between OIH and chronic migraine occur through neuropeptide dysregulation. Using label-...
Autores principales: | Anapindi, Krishna D.B., Yang, Ning, Romanova, Elena V., Rubakhin, Stanislav S., Tipton, Alycia, Dripps, Isaac, Sheets, Zoie, Sweedler, Jonathan V., Pradhan, Amynah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885698/ https://www.ncbi.nlm.nih.gov/pubmed/31649062 http://dx.doi.org/10.1074/mcp.RA119.001767 |
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