Absolute Quantification of Apolipoproteins Following Treatment with Omega-3 Carboxylic Acids and Fenofibrate Using a High Precision Stable Isotope-labeled Recombinant Protein Fragments Based SRM Assay

Stable isotope-labeled standard (SIS) peptides are used as internal standards in targeted proteomics to provide robust protein quantification, which is required in clinical settings. However, SIS peptides are typically added post trypsin digestion and, as the digestion efficiency can vary significan...

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Detalles Bibliográficos
Autores principales: Hober, Andreas, Edfors, Fredrik, Ryaboshapkina, Maria, Malmqvist, Jonas, Rosengren, Louise, Percy, Andrew J., Lind, Lars, Forsström, Björn, Uhlén, Mathias, Oscarsson, Jan, Miliotis, Tasso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885709/
https://www.ncbi.nlm.nih.gov/pubmed/31591263
http://dx.doi.org/10.1074/mcp.RA119.001765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885709/
https://www.ncbi.nlm.nih.gov/pubmed/31591263
http://dx.doi.org/10.1074/mcp.RA119.001765

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