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Absolute Quantification of Apolipoproteins Following Treatment with Omega-3 Carboxylic Acids and Fenofibrate Using a High Precision Stable Isotope-labeled Recombinant Protein Fragments Based SRM Assay
Stable isotope-labeled standard (SIS) peptides are used as internal standards in targeted proteomics to provide robust protein quantification, which is required in clinical settings. However, SIS peptides are typically added post trypsin digestion and, as the digestion efficiency can vary significan...
Autores principales: | Hober, Andreas, Edfors, Fredrik, Ryaboshapkina, Maria, Malmqvist, Jonas, Rosengren, Louise, Percy, Andrew J., Lind, Lars, Forsström, Björn, Uhlén, Mathias, Oscarsson, Jan, Miliotis, Tasso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885709/ https://www.ncbi.nlm.nih.gov/pubmed/31591263 http://dx.doi.org/10.1074/mcp.RA119.001765 |
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