Downregulating Serine Hydroxymethyltransferase 2 Deteriorates Hepatic Ischemia-Reperfusion Injury through ROS/JNK/P53 Signaling in Mice

BACKGROUND: Serine hydroxymethyltransferase 2 (SHMT2) activity ensures that cells have a survival advantage in ischemic conditions and regulates redox homeostasis. In this study, we aimed to investigate the role of SHMT2 after hepatic ischemia-reperfusion (IR), which involves hypoxia, ischemic condi...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Bai, He, Duan, Shigang, Yuan, Fangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885790/
https://www.ncbi.nlm.nih.gov/pubmed/31828098
http://dx.doi.org/10.1155/2019/2712185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885790/
https://www.ncbi.nlm.nih.gov/pubmed/31828098
http://dx.doi.org/10.1155/2019/2712185

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