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Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health

Glycation, oxidation, nitration, and crosslinking of proteins are implicated in the pathogenic mechanisms of type 2 diabetes, cardiovascular disease, and chronic kidney disease. Related modified amino acids formed by proteolysis are excreted in urine. We quantified urinary levels of these metabolite...

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Detalles Bibliográficos
Autores principales: Masania, Jinit, Faustmann, Gernot, Anwar, Attia, Hafner-Giessauf, Hildegard, Rajpoot, Nasir, Grabher, Johanna, Rajpoot, Kashif, Tiran, Beate, Obermayer-Pietsch, Barbara, Winklhofer-Roob, Brigitte M., Roob, Johannes M., Rabbani, Naila, Thornalley, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885816/
https://www.ncbi.nlm.nih.gov/pubmed/31827677
http://dx.doi.org/10.1155/2019/4851323