Cargando…

Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health

Glycation, oxidation, nitration, and crosslinking of proteins are implicated in the pathogenic mechanisms of type 2 diabetes, cardiovascular disease, and chronic kidney disease. Related modified amino acids formed by proteolysis are excreted in urine. We quantified urinary levels of these metabolite...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masania, Jinit, Faustmann, Gernot, Anwar, Attia, Hafner-Giessauf, Hildegard, Rajpoot, Nasir, Grabher, Johanna, Rajpoot, Kashif, Tiran, Beate, Obermayer-Pietsch, Barbara, Winklhofer-Roob, Brigitte M., Roob, Johannes M., Rabbani, Naila, Thornalley, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885816/ https://www.ncbi.nlm.nih.gov/pubmed/31827677 http://dx.doi.org/10.1155/2019/4851323

Ejemplares similares

Increased DNA Dicarbonyl Glycation and Oxidation Markers in Patients with Type 2 Diabetes and Link to Diabetic Nephropathy
por: Waris, Sahar, et al.
Publicado: (2015)

Progesterone-associated arginine decline at luteal phase of menstrual cycle and associations with related amino acids and nuclear factor kB activation
por: Faustmann, Gernot, et al.
Publicado: (2018)

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
por: Masania, Jinit, et al.
Publicado: (2022)

Advanced glycation endproducts, dityrosine and arginine transporter dysfunction in autism - a source of biomarkers for clinical diagnosis
por: Anwar, Attia, et al.
Publicado: (2018)

Glycation marker glucosepane increases with the progression of osteoarthritis and correlates with morphological and functional changes of cartilage in vivo
por: Legrand, Catherine, et al.
Publicado: (2018)

Protein oxidation, nitration and glycation biomarkers for early-stage diagnosis of osteoarthritis of the knee and typing and progression of arthritic disease
por: Ahmed, Usman, et al.
Publicado: (2016)

Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance
por: Thornalley, Paul J., et al.
Publicado: (2010)

An Introduction to the Special Issue “Protein Glycation in Food, Nutrition, Health and Disease”
por: Rabbani, Naila, et al.
Publicado: (2022)

Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors
por: Rabbani, Naila, et al.
Publicado: (2022)

Mass spectrometric determination of early and advanced glycation in biology
por: Rabbani, Naila, et al.
Publicado: (2016)

Dicarbonyl stress, protein glycation and the unfolded protein response
por: Rabbani, Naila, et al.
Publicado: (2021)

Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
por: Rabbani, Naila, et al.
Publicado: (2021)

Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover
por: Rabbani, Naila, et al.
Publicado: (2020)

Functional Connectivity Alterations in Epilepsy from Resting-State Functional MRI
por: Rajpoot, Kashif, et al.
Publicado: (2015)

Dicarbonyl stress in clinical obesity
por: Masania, Jinit, et al.
Publicado: (2016)

Multicentric Validation of Proteomic Biomarkers in Urine Specific for Diabetic Nephropathy
por: Alkhalaf, Alaa, et al.
Publicado: (2010)

Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress
por: Kurz, Alexander, et al.
Publicado: (2010)

Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity: A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes
por: Rabbani, Naila, et al.
Publicado: (2011)

Glyoxalase 1 copy number variation in patients with well differentiated gastro-entero-pancreatic neuroendocrine tumours (GEP-NET)
por: Xue, Mingzhan, et al.
Publicado: (2017)

Increased Glycation and Oxidative Damage to Apolipoprotein B100 of LDL Cholesterol in Patients With Type 2 Diabetes and Effect of Metformin
por: Rabbani, Naila, et al.
Publicado: (2010)

Early renal dysfunction and fibroblast growth factor-23 in patients with small vessel disease-related stroke
por: Fandler-Höfler, Simon, et al.
Publicado: (2019)

Does aging affect the immune status? A comparative analysis in 300 healthy volunteers from France, Austria and Spain
por: Vasson, Marie-Paule, et al.
Publicado: (2013)

Subclinical inflammation, telomere shortening, homocysteine, vitamin B6, and mortality: the Ludwigshafen Risk and Cardiovascular Health Study
por: Pusceddu, Irene, et al.
Publicado: (2019)

High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes
por: Perkins, Bruce A., et al.
Publicado: (2020)

Advanced Glycation End Products in Extracellular Matrix Proteins Contribute to the Failure of Sensory Nerve Regeneration in Diabetes
por: Duran-Jimenez, Beatriz, et al.
Publicado: (2009)

AGEomics Biomarkers and Machine Learning—Realizing the Potential of Protein Glycation in Clinical Diagnostics
por: Rabbani, Naila
Publicado: (2022)

Arginine-directed glycation and decreased HDL plasma concentration and functionality
por: Godfrey, L, et al.
Publicado: (2014)

Serum Levels of Advanced Glycation Endproducts and Other Markers of Protein Damage in Early Diabetic Nephropathy in Type 1 Diabetes
por: Perkins, Bruce A., et al.
Publicado: (2012)

Subcellular protein expression models for microsatellite instability in colorectal adenocarcinoma tissue images
por: Kovacheva, Violeta N., et al.
Publicado: (2016)

Neutrophils are immune cells preferentially targeted by retinoic acid in elderly subjects
por: Minet-Quinard, Régine, et al.
Publicado: (2010)

Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics
por: Rabbani, Naila, et al.
Publicado: (2016)

Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes
por: Rabbani, Naila, et al.
Publicado: (2022)

Deep Learning With Sampling in Colon Cancer Histology
por: Shapcott, Mary, et al.
Publicado: (2019)

Analysis of Serum Advanced Glycation Endproducts Reveals Methylglyoxal-Derived Advanced Glycation MG-H1 Free Adduct Is a Risk Marker in Non-Diabetic and Diabetic Chronic Kidney Disease
por: Rabbani, Naila, et al.
Publicado: (2022)

Automated analysis for multiplet identification from ultra-high resolution 2D- (1)H, (13)C-HSQC NMR spectra
por: Ferrante, Laura, et al.
Publicado: (2023)

A model of the spatial tumour heterogeneity in colorectal adenocarcinoma tissue
por: Kovacheva, Violeta N., et al.
Publicado: (2016)

Examination of the Effects of Conduction Slowing on the Upstroke of Optically Recorded Action Potentials
por: O’Shea, Christopher, et al.
Publicado: (2019)

Statistical mediation of the relationships between chronological age and lipoproteins by nonessential amino acids in healthy men
por: Mallol, Roger, et al.
Publicado: (2021)

A gamma-gaussian mixture model for detection of mitotic cells in breast cancer histopathology images
por: Khan, Adnan Mujahid, et al.
Publicado: (2013)

Artificial Intelligence-based methods in head and neck cancer diagnosis: an overview
por: Mahmood, Hanya, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fa1jiiassmndu189u2s75eo4ob