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Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids

Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. To add built-in immune function, coculture of the dorsal forebrain spheroids with isogenic m...

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Detalles Bibliográficos
Autores principales: Bejoy, Julie, Yuan, Xuegang, Song, Liqing, Hua, Thien, Jeske, Richard, Sart, Sébastien, Sang, Qing-Xiang Amy, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885849/
https://www.ncbi.nlm.nih.gov/pubmed/31827525
http://dx.doi.org/10.1155/2019/2382534