Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion

BACKGROUND: Podosomes are membrane‐bound adhesive structures formed by actin remodeling. They are capable of extracellular matrix (ECM) degradation, which is a prerequisite for cancer cell invasion and metastasis. The signaling mechanism of podosome formation is still unknown in cancer. We previousl...

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Detalles Bibliográficos
Autores principales: Chaki, Sankar P., Barhoumi, Rola, Rivera, Gonzalo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885876/
https://www.ncbi.nlm.nih.gov/pubmed/31638742
http://dx.doi.org/10.1002/cam4.2640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885876/
https://www.ncbi.nlm.nih.gov/pubmed/31638742
http://dx.doi.org/10.1002/cam4.2640

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