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Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion
BACKGROUND: Podosomes are membrane‐bound adhesive structures formed by actin remodeling. They are capable of extracellular matrix (ECM) degradation, which is a prerequisite for cancer cell invasion and metastasis. The signaling mechanism of podosome formation is still unknown in cancer. We previousl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885876/ https://www.ncbi.nlm.nih.gov/pubmed/31638742 http://dx.doi.org/10.1002/cam4.2640 |