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Exploring the 2D and 3D structural properties of topologically associating domains

BACKGROUND: Topologically associating domains (TADs) are genomic regions with varying lengths. The interactions within TADs are more frequent than those between different TADs. TADs or sub-TADs are considered the structural and functional units of the mammalian genomes. Although TADs are important f...

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Detalles Bibliográficos
Autores principales: Liu, Tong, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886161/
https://www.ncbi.nlm.nih.gov/pubmed/31787081
http://dx.doi.org/10.1186/s12859-019-3083-z