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CRISPR-Cas13d mediates robust RNA virus interference in plants

BACKGROUND: CRISPR-Cas systems endow bacterial and archaeal species with adaptive immunity mechanisms to fend off invading phages and foreign genetic elements. CRISPR-Cas9 has been harnessed to confer virus interference against DNA viruses in eukaryotes, including plants. In addition, CRISPR-Cas13 s...

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Detalles Bibliográficos
Autores principales: Mahas, Ahmed, Aman, Rashid, Mahfouz, Magdy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886189/
https://www.ncbi.nlm.nih.gov/pubmed/31791381
http://dx.doi.org/10.1186/s13059-019-1881-2