Joint between-sample normalization and differential expression detection through ℓ(0)-regularized regression

BACKGROUND: A fundamental problem in RNA-seq data analysis is to identify genes or exons that are differentially expressed with varying experimental conditions based on the read counts. The relativeness of RNA-seq measurements makes the between-sample normalization of read counts an essential step i...

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Detalles Bibliográficos
Autores principales: Liu, Kefei, Shen, Li, Jiang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886201/
https://www.ncbi.nlm.nih.gov/pubmed/31787074
http://dx.doi.org/10.1186/s12859-019-3070-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886201/
https://www.ncbi.nlm.nih.gov/pubmed/31787074
http://dx.doi.org/10.1186/s12859-019-3070-4

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