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DNA methylation and miRNA-1296 act in concert to mediate spatiotemporal expression of KPNA7 during bovine oocyte and early embryonic development

BACKGROUND: Epigenetic regulation of oocyte-specific maternal factors is essential for oocyte and early embryonic development. KPNA7 is an oocyte-specific maternal factor, which controls transportation of nuclear proteins important for early embryonic development. To elucidate the epigenetic mechani...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Hand, Jacqelyn M., Fu, Liyuan, Smith, George W., Yao, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886206/
https://www.ncbi.nlm.nih.gov/pubmed/31787077
http://dx.doi.org/10.1186/s12861-019-0204-x