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Stochastic transcription in the p53‐mediated response to DNA damage is modulated by burst frequency
Discontinuous transcription has been described for different mammalian cell lines and numerous promoters. However, our knowledge of how the activity of individual promoters is adjusted by dynamic signaling inputs from transcription factors is limited. To address this question, we characterized the a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886302/ https://www.ncbi.nlm.nih.gov/pubmed/31885199 http://dx.doi.org/10.15252/msb.20199068 |