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Bone marrow endothelial cell-derived interleukin-4 contributes to thrombocytopenia in acute myeloid leukemia

Normal hematopoiesis can be disrupted by the leukemic bone marrow microenvironment, which leads to cytopenia-associated symptoms including anemia, hemorrhage and infection. Thrombocytopenia is a major and sometimes fatal complication in patients with acute leukemia. However, the mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: Gao, Ai, Gong, Yuemin, Zhu, Caiying, Yang, Wanzhu, Li, Qing, Zhao, Mei, Ma, Shihui, Li, Jianyong, Hao, Sha, Cheng, Hui, Cheng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886411/
https://www.ncbi.nlm.nih.gov/pubmed/30792200
http://dx.doi.org/10.3324/haematol.2018.214593