T Regulatory Cells From Non-obese Diabetic Mice Show Low Responsiveness to IL-2 Stimulation and Exhibit Differential Expression of Anergy-Related and Ubiquitination Factors

Foxp3+ Regulatory T cells (Tregs) are pivotal for the maintenance of tolerance. Alterations in their number and/or function have been proposed to occur in the autoimmune-prone non-obese diabetic (NOD) mouse. Comparing the frequencies and absolute numbers of CD4+Foxp3+CD25+ Tregs among 4 to 6-week ol...

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Detalles Bibliográficos
Autores principales: Godoy, Gloria J., Olivera, Carolina, Paira, Daniela A., Salazar, Florencia C., Ana, Yamile, Stempin, Cinthia C., Motrich, Ruben D., Rivero, Virginia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886461/
https://www.ncbi.nlm.nih.gov/pubmed/31824482
http://dx.doi.org/10.3389/fimmu.2019.02665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886461/
https://www.ncbi.nlm.nih.gov/pubmed/31824482
http://dx.doi.org/10.3389/fimmu.2019.02665

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