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Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging

Aging is a pleiotropic process affecting many aspects of mammalian physiology. Mammals are composed of distinct cell type identities and tissue environments, but the influence of these cell identities and environments on the trajectory of aging in individual cells remains unclear. Here, we performed...

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Detalles Bibliográficos
Autores principales: Kimmel, Jacob C., Penland, Lolita, Rubinstein, Nimrod D., Hendrickson, David G., Kelley, David R., Rosenthal, Adam Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886498/
https://www.ncbi.nlm.nih.gov/pubmed/31754020
http://dx.doi.org/10.1101/gr.253880.119