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Simvastatin Evokes An Unpredicted Antagonism For Tamoxifen In MCF-7 Breast Cancer Cells

PURPOSE: Tamoxifen (TAM) is a non-steroidal antiestrogen drug, used in the prevention and treatment of all stages of hormone-responsive breast cancer. Simvastatin (SIM) is a lipid-lowering agent and has been shown to inhibit cancer cell growth. The study aimed to investigate the effect of the combin...

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Detalles Bibliográficos
Autores principales: Ibrahim, Amel B, Zaki, Hala F, Wadie, Walaa, Omran, Mervat M, Shouman, Samia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886548/
https://www.ncbi.nlm.nih.gov/pubmed/31819634
http://dx.doi.org/10.2147/CMAR.S218668