DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression

The DUX4 transcription factor is briefly expressed in the early cleavage-stage embryo, where it induces an early wave of zygotic gene transcription, whereas its mis-expression in skeletal muscle causes the muscular dystrophy facioscapulohumeral dystrophy (FSHD). Here, we show that DUX4 induces the e...

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Detalles Bibliográficos
Autores principales: Resnick, Rebecca, Wong, Chao-Jen, Hamm, Danielle C., Bennett, Sean R., Skene, Peter J., Hake, Sandra B., Henikoff, Steven, van der Maarel, Silvère M., Tapscott, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886682/
https://www.ncbi.nlm.nih.gov/pubmed/31722199
http://dx.doi.org/10.1016/j.celrep.2019.10.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886682/
https://www.ncbi.nlm.nih.gov/pubmed/31722199
http://dx.doi.org/10.1016/j.celrep.2019.10.025

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