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DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression
The DUX4 transcription factor is briefly expressed in the early cleavage-stage embryo, where it induces an early wave of zygotic gene transcription, whereas its mis-expression in skeletal muscle causes the muscular dystrophy facioscapulohumeral dystrophy (FSHD). Here, we show that DUX4 induces the e...
Autores principales: | Resnick, Rebecca, Wong, Chao-Jen, Hamm, Danielle C., Bennett, Sean R., Skene, Peter J., Hake, Sandra B., Henikoff, Steven, van der Maarel, Silvère M., Tapscott, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886682/ https://www.ncbi.nlm.nih.gov/pubmed/31722199 http://dx.doi.org/10.1016/j.celrep.2019.10.025 |
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