In-situ observation of conformational dynamics and protein-ligand/substrate interactions in outer membrane proteins with DEER/PELDOR spectroscopy

Observing structure and conformational dynamics of membrane proteins at high-resolution in their native environments is challenging because of the lack of suitable techniques. We have developed an approach for high-precision distance measurements in the nanometer range for outer membrane proteins (O...

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Detalles Bibliográficos
Autores principales: Joseph, Benesh, Jaumann, Eva A, Sikora, Arthur, Barth, Katja, Prisner, Thomas F, Cafiso, David S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886689/
https://www.ncbi.nlm.nih.gov/pubmed/31278399
http://dx.doi.org/10.1038/s41596-019-0182-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886689/
https://www.ncbi.nlm.nih.gov/pubmed/31278399
http://dx.doi.org/10.1038/s41596-019-0182-2

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