NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8(+) T Cells

Autophagy plays a critical role in the maintenance of immunological memory. However, the molecular mechanisms involved in autophagy-regulated effector memory formation in CD8(+) T cells remain unclear. Here we show that deficiency in NIX-dependent mitophagy leads to metabolic defects in effector mem...

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Detalles Bibliográficos
Autores principales: Gupta, Shubhranshu S., Sharp, Robert, Hofferek, Colby, Kuai, Le, Dorn, Gerald W., Wang, Jin, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886713/
https://www.ncbi.nlm.nih.gov/pubmed/31722203
http://dx.doi.org/10.1016/j.celrep.2019.10.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886713/
https://www.ncbi.nlm.nih.gov/pubmed/31722203
http://dx.doi.org/10.1016/j.celrep.2019.10.032

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