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Optimization of TripleTOF spectral simulation and library searching for confident localization of phosphorylation sites

Tandem mass spectrometry (MS/MS) has been used in analysis of proteins and their post-translational modifications. A recently developed data analysis method, which simulates MS/MS spectra of phosphopeptides and performs spectral library searching using SpectraST, facilitates confident localization o...

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Detalles Bibliográficos
Autores principales: Takai, Ayano, Tsubosaka, Tomoya, Hirano, Yasuhiro, Hayakawa, Naoki, Tani, Fumitaka, Haapaniemi, Pekka, Suni, Veronika, Imanishi, Susumu Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886777/
https://www.ncbi.nlm.nih.gov/pubmed/31790495
http://dx.doi.org/10.1371/journal.pone.0225885