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Optimization of TripleTOF spectral simulation and library searching for confident localization of phosphorylation sites
Tandem mass spectrometry (MS/MS) has been used in analysis of proteins and their post-translational modifications. A recently developed data analysis method, which simulates MS/MS spectra of phosphopeptides and performs spectral library searching using SpectraST, facilitates confident localization o...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886777/ https://www.ncbi.nlm.nih.gov/pubmed/31790495 http://dx.doi.org/10.1371/journal.pone.0225885 |