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Formation of a structurally-stable conformation by the intrinsically disordered MYC:TRRAP complex
Our primary goal is to therapeutically target the oncogenic transcription factor MYC to stop tumor growth and cancer progression. Here, we report aspects of the biophysical states of the MYC protein and its interaction with one of the best-characterized MYC cofactors, TRansactivation/tRansformation-...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886782/ https://www.ncbi.nlm.nih.gov/pubmed/31790487 http://dx.doi.org/10.1371/journal.pone.0225784 |