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Formation of a structurally-stable conformation by the intrinsically disordered MYC:TRRAP complex

Our primary goal is to therapeutically target the oncogenic transcription factor MYC to stop tumor growth and cancer progression. Here, we report aspects of the biophysical states of the MYC protein and its interaction with one of the best-characterized MYC cofactors, TRansactivation/tRansformation-...

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Detalles Bibliográficos
Autores principales:	Feris, Edmond J., Hinds, John W., Cole, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886782/ https://www.ncbi.nlm.nih.gov/pubmed/31790487 http://dx.doi.org/10.1371/journal.pone.0225784

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