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Contrasting the impact of cytotoxic and cytostatic drug therapies on tumour progression

A tumour grows when the total division (birth) rate of its cells exceeds their total mortality (death) rate. The capability for uncontrolled growth within the host tissue is acquired via the accumulation of driver mutations which enable the tumour to progress through various hallmarks of cancer. We...

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Detalles Bibliográficos
Autores principales: Anttila, Jani V., Shubin, Mikhail, Cairns, Johannes, Borse, Florian, Guo, Qingli, Mononen, Tommi, Vázquez-García, Ignacio, Pulkkinen, Otto, Mustonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886869/
https://www.ncbi.nlm.nih.gov/pubmed/31738747
http://dx.doi.org/10.1371/journal.pcbi.1007493