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A meta-analysis of genome-wide association studies of epigenetic age acceleration

'Epigenetic age acceleration' is a valuable biomarker of ageing, predictive of morbidity and mortality, but for which the underlying biological mechanisms are not well established. Two commonly used measures, derived from DNA methylation, are Horvath-based (Horvath-EAA) and Hannum-based (H...

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Detalles Bibliográficos
Autores principales: Gibson, Jude, Russ, Tom C., Clarke, Toni-Kim, Howard, David M., Hillary, Robert F., Evans, Kathryn L., Walker, Rosie M., Bermingham, Mairead L., Morris, Stewart W., Campbell, Archie, Hayward, Caroline, Murray, Alison D., Porteous, David J., Horvath, Steve, Lu, Ake T., McIntosh, Andrew M., Whalley, Heather C., Marioni, Riccardo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886870/
https://www.ncbi.nlm.nih.gov/pubmed/31738745
http://dx.doi.org/10.1371/journal.pgen.1008104